This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Related article  • Related letters  • Similar articles in JAMA  Topic Collections  • Nutritional and Metabolic Disorders  • Metabolic Diseases  • Psychiatry  • Depression  • Endocrine Diseases  • Diabetes Mellitus  • Alert me on articles by topic  Social Bookmarking   What's this?

	Since this article does not have an abstract, we have provided the first 123 words of the full text and any section headings.

To the Editor: The study by Dr Golden and colleagues¹ showed that baseline depressive symptoms were associated with subsequent incidence of type 2 diabetes. Additionally, treated type 2 diabetes was associated with subsequent depressive symptoms.

However, evaluating the association between diabetes and incident depressive symptoms should take into account that affective diseases such as recurrent major depressive disorder and bipolar disorder can fully remit between episodes. Thus, the absence of depressive symptoms during a 1-week time frame could represent a state of a remitted bipolar or recurrent depressive disorder. To investigate diabetes as a possible risk factor for the development of depressive disorder, the authors should have assessed whether there were manic or major depressive episodes before study enrollment.

Financial Disclosures: None reported.

Olaf Schulte-Herbrüggen, MD
olaf.schulte-herbrueggen@charite.de

Scharif Bahri, MD; Stefan Röpke, MD
Department of Psychiatry and Psychotherapy
Charité-University Medicine Berlin
Berlin, Germany

1. Golden SH, Lazo M, Carnethon M; et al. Examining a bidirectional association between depressive symptoms and diabetes. JAMA. 2008;299(23):2751-2759. FREE FULL TEXT

JAMA. 2008;300(18):2115.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati     What's this?

RELATED ARTICLE

Examining a Bidirectional Association Between Depressive Symptoms and Diabetes
Sherita Hill Golden, Mariana Lazo, Mercedes Carnethon, Alain G. Bertoni, Pamela J. Schreiner, Ana V. Diez Roux, Hochang Benjamin Lee, and Constantine Lyketsos
JAMA. 2008;299(23):2751-2759.
ABSTRACT | FULL TEXT  

RELATED LETTERS

Depressive Symptoms and Diabetes
David E. Kemp, Joseph R. Calabrese, and Faramarz Ismail-Beigi
JAMA. 2008;300(18):2115-2116.
EXTRACT | FULL TEXT  

Depressive Symptoms and Diabetes—Reply
Sherita Hill Golden and Mercedes R. Carnethon
JAMA. 2008;300(18):2116.
EXTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

``Worried all the time'': distress and the circumstances of everyday life among immigrant Australians with type 2 Diabetes
Manderson and Kokanovic
Chronic Illness 2009;5:21-32.
ABSTRACT